Study challenges old notion that menopause starts in the ovariesSome of
the most unpleasant symptoms of menopause, such as hot flashes and night
sweats, have long been believed to originate in the ovaries.
But new research challenges that assumption, and instead suggests that
menopausal symptoms, at least in part, may begin in the brain.
That's because the hypothalamus and the pituitary gland stop reacting
normally to estrogen in some women, suggesting they may have developed a
reduced sensitivity to estrogen, researchers at the New Jersey Medical
School report in the Dec. 22/29 issue of the Journal of the American
Medical Association.
"This is an important new concept: Menopause doesn't just originate in
the ovary, but also in the brain," said Laura Goldsmith, a professor of
obstetrics and gynecology and women's he
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